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Original Article

Vaccine and mycostatin in treatment of cryptococcosis of the respiratory tract

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Pages 171-179 | Published online: 09 Jul 2009
 

Abstract

Three cases of respiratory cryptococcosis are described, one diagnosed only after thoracotomy and two after cytology. All were confirmed by cultures, biological and biochemical tests. The patients are alive and well 14 years, 5 years, and 5 years after treatment with cryptococcal vaccines and mycostatin. Vaccines proved very effective when given intradermally in small doses and no dangerous reactions were encountered. Cytology of the sputum appears to be a very useful tool in diagnosis of fungal infections of the respiratory tract, especially when supravital staining is used. Difficulties in diagnosis, treatment, and significance of positive sputum findings are discussed.

Zusammenfassung

Es werden drei Kryptokokkose Fälle der Atemorgane bescreiben, die durch Kulturen, biochemische und biologische Teste bestätigt wurden. Einige Jahre nach der Behandlung mit Kryptokokkal-Vaccinen und Mycostatin, fühlen sich alle drei Patienten wohl. Es ist anzunehmen dass die Vaccine wenn sie in kleinen Dosen intradermal verabreicht werden, sich gut auswirkt.

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