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Original Article

Cell mediated immune response in human cases of rhinosporidiosis

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Pages 135-142 | Received 27 Oct 1980, Accepted 19 Dec 1980, Published online: 09 Jul 2009
 

Abstract

Leukocyte migration inhibition (LMI) and T lymphocyte counts were used as measures of cell mediated immunity in 37 patients with rhinosporidiosis and 18 healthy individuals. LMI was higher in all the patients than the normal controls, and it was maximal in patients with infection of 3–9 years' duration. When the chronicity of infection exceeded 10 years, there was a fall in LMI response although it was still more than that of the normal controls. The T cell count was significantly low with infection of 1–2 years' duration than in normals, but it rose to normal values in patients with infection that had lasted 3 years or more.

Résumé

L'inhibition de la migration des leucocytes (IML) et des T-lymphocytes à été utilisée pour mesurer l'immunité cellulaire chez 37 malades à rhinosporidiose et chez 18 individus sains. L' IML est plus forte chez les malades que chez les contrôles et elle atteinte un maximum chez les malades infectés depuis 3 à 9 ans. Quand la chronicité de la maladie dépasse 10 ans, on observe une chute de l' IML quoiqu'elle reste supérieure à celle des contrôles. La numération des cellules T est significativement plus basse dans les infections d'une durée de 1 à 2 ans que chez les contrôles mais elle remonte à des valeurs normales chez les malades dont l'infection date de plus de 3 ans.

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