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Original Article

Isolation of a Candida albicans mutant with reduced content of cell wall mannan and deficient mannan phosphorylation

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Pages 315-321 | Accepted 21 Mar 1984, Published online: 09 Jul 2009
 

Abstract

A rough-colony mutant of Candida albicans was isolated after ultraviolet mutagenesis. The mutant contained approximately half the normal amount of the cell wall mannan, the acetolysis pattern of which was indistinguishable from that of the wild-type counterpart. However, the extent of phosphorylation in the mutant mannan was about 12% of the value for wild type.

Zusammenfassung

Eine rauh-wachsende Kolonie von Candida albicans wurde nach UV-Mutagenese isoliert. Die Mutante enthielt nur halb soviel Mannan in der Zellwand wie der Wildtyp. Das Acetolyse-Muster der beiden (Mutante-Wildtyp) Mannane war nicht unterscheidbar. Dagegen war der Grad der Phosphorylation des Mannan der Mutante nur 12% des Wertes vom Wildtyp.

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