Application of Neutron Activation Paper Chromatographic Analysis of Phospholipids in Clinical Investigation¹

Abstract

The application of neutron activation paper chromatography has been shown to be most suitable for the analysis of phospholipids in clinical research where labelling of phospholipids with P³² is not possible and only a minute amount of sample is available.

This technique made it possible for the first time to analyze phospholipids in human liver biopsy samples and a comparison was made between human liver and plasma phospholipids. Much less phosphatidylethanola-mine and phosphoinositide were found in human plasma.

Further evidence was presented for the presence of lysolecithin in human plasma.