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Original Article

On the Effect of Alimentary Lipemia and a Natural Heparinoid on the Fibrinolytic System of Man

Pages 87-99 | Received 15 Apr 1961, Published online: 28 Aug 2009
 

Abstract

The effect of alimentary lipemia and Ateroid on the fibrinolytic system of blood was studied in 12 patients. The plasminogen (profibrinolysin), proactivator and antiplasmin activities were determined by the clot lysis time-method.

Lipemia had an inhibiting effect on the fibrinolytic system. This appeared most distinctly in the antiplasmin determinations. In the. In the pre-therapeutic fat load tests the changes in the antiplasmin activity differed statistically significantly from those observed during therapy. Ateroid seemed to protect the organism against the antiplasmin effect of lipemia.

The female fibrinolytic system seemed to react more sensitively than the male.

The effect of Ateroid on the fibrinolytic system seems to be first and foremost a nor-malising influence: it appears most distincly in exceptional circumstances and is very distinct if the divergence is due to hyperlipemia.

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