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Abstract
In 9 groups of liver diseases, 11 serum protein parameters were studied. Prealbumin, retinol-binding protein, albumin, a-lipoprotein and Normotest® (NT) were usually highly intercorrelated and separated best among groups with different types of functional impairment. Haptoglobin, C3 and total iron-binding capacity were probably also sometimes reduced by restricted protein synthesis but appeared to be more easily affected by other factors, α1-antitrypsin was often increased in different liver diseases, but a pattern compatible with the ‘acute-phase reaction’ was regularly present only in hepatic tumors. Bile retention was often accompanied by relatively high levels of ceruloplasmin, C3, and α-lipoprotein and by high NT values.