Activity of creatine kinase isoenzymes in the serum after acute alcohol intake and in chronic alcoholism

Abstract

The activities of CK and its isoenzymes were determined in the sera of six test subjects just before, and 6 and 24 h after, alcohol intake. The CK activity was higher after alcohol intake, but the change was not significant. CK-MB isoenzyme was not observed. The activities of CK and its isoenzymes were also determined in serum from 14 chronic alcoholics, who had consumed alcohol for several days before the blood sampling. Pathologically high activity of creatine kinase was found in six of them, but CK-MB and CK-BB isoenzymes were not found.

Key-words:

• alcoholic cardiomyopathy
• creatine kinase isoenzymes
• heart infarction
• muscle enzyme