5
Views
1
CrossRef citations to date
0
Altmetric
Original Article

Total and ionized calcium levels during open heart surgery with two different pump priming solutions

, , , , &
Pages 111-114 | Published online: 17 Mar 2010
 

Abstract

Changes of total (Ca) and ionized Ca-levels (Ca2+) were studied during open heart surgery in 18 patients. 9 patients (group A) had only cristalloid solutions as pump priming, the other 9 patients (group B) had 500 ml of titrated whole blood in the priming solution. For assessment of hemodilution hct and total plasma protein and plasma albumin were determined. Measurements were done preoperatively, before and after systemic heparinisation, during and after extracorporeal circulation (ECC) and on the first postoperative day.

Results:

Anticoagulation with 375 U/kg BW heparin had no effect on ionized calcium levels.

With onset of ECC (Ca) decreased by 30% in group A and by 20% in group B. (Ca2+), however, decreased by 20% in group A and by 35% in group B. The percentage of ionized calcium increased by 15% in group A whereas it decreased by the same amount in group B.

This difference is contributed to the calcium binding effect of citrate added to pump priming in group B. Mechanisms of the relative increase of ionized calcium during ECC in group A, however, remain to be studied.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.