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Original Article

On the contamination of commercially available aprotinins with pancreatic islet peptides

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Pages 669-672 | Received 31 Mar 1984, Accepted 12 Jun 1984, Published online: 28 Aug 2009
 

Abstract

Contamination of aprotinins with immunoreactive insulin. glicentin, glucagon, somatostatin, pancreatic polypeptide and pancreatic polypeptide-icosapeptide was estimated by radioimmunoassay. High somatostatin concentrations were found in two commercial preparations. Influence of somatostatin contamination of aprotinins on the clinical as well as the laboratory applications of aprotinin may thus be anticipated.

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