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Original Article

Atrial natriuretic peptide in relation to physical exercise

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Pages 681-683 | Received 30 Jan 1987, Accepted 24 Apr 1987, Published online: 17 Mar 2010
 

Abstract

The effect of physical exercise on atrial natriuretic peptide (ANP) was studied in 10 healthy young volunteers. The subjects were exercised on a bicycle ergometry until exhaustion. Blood samples were drawn at rest, at maximal load and in the following resting period. ANP concentrations were measured by radio-immunoassay. The level of ANP rose from 6.7±0.5 at rest to 33.2±7.0 pmol/1 (mean±SEM) (p<0.05) at maximal load and returned to normal after 45 min. It was not possible to demonstrate a correlation between a change in ANP concentration and changes in pulse rate, blood pressure, maximal physical load, volume of urine, the amount of urine sodium, urine potassium or urine creatinine during the exercise load.

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