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Scandinavian Journal of Gastroenterology Volume 36, 2001 - Issue 3
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Research Article

A New Fecal Calprotectin Test for Colorectal Neoplasia: Clinical Results and Comparison with Previous Method

B. Johne, O. Kronborg, H. I. Tøn, J. Kristinsson, P. Fuglerud Axis-Shield ASA, Oslo, Norway
Pages 291-296 | Published online: 08 Jul 2009
 
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Abstract

Background: Fecal calprotectin is elevated in patients with colorectal cancer (CRC). An improved method has been developed. The aim was to evaluate sensitivity and specificity for CRC with the new fecal calprotectin method and to compare the results with those of the original method. Methods: The study comprised 453 subjects including symptomatic CRC patients and CRC high risk subjects with and without CRC. Complete colonoscopy was performed. Calprotectin was measured with an enzyme linked immunosorbent assay (ELISA) using small (50-100 mg) feces samples. Results:

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