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Case Report

Sarcoidosis in untreated chronic hepatitis C virus infection

, , , &
Pages 401-403 | Received 03 Sep 2003, Accepted 23 Dec 2003, Published online: 08 Jul 2009
 

Abstract

Chronic hepatitis C has been implicated in the pathogenesis of sarcoidosis in several cases of patients treated with interferon‐α. On the other hand, only in a few cases previously has a possible link between sarcoidosis and untreated chronic hepatitis C virus infection been demonstrated. We report on a patient with chronic hepatitis C who developed cutaneous sarcoidosis without prior interferon‐α treatment. We hypothesize that viral persistence seen in chronic hepatitis C virus infection might be one of the potential factors that trigger cellular immune response in granulomatous reactions as seen in sarcoidosis, in genetically predisposed patients.

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