Transperitoneal Exchange

Abstract

Aune, S. 1970. Transperitoncal Exchange. I. Peritoneal Permeability Studied by Transperitoneal Plasma Clearance of Urea, PAH, Inulin, and Serum Albumin in Rabbits. Scand. J. Gastroent. 5, 85-97.

The transfer of urea, PAH, inulin, and serum albumin from plasma into the peritoneal cavity were recorded in order to characterize the blood-peritoneal barrier. Relative clearance rates were found according to the diffusibility of each substance. Thus no selective restriction of the passage of the indicator substances could be demonstrated. The results failed to describe the permeability by means of pores and indicated that the peritoneal membrane is leaky. Solutes pass either by diffusion alone or by combined diffusion and the solvent drag effect of a convective fluid flow. Some degree of blood flow limitation of the plasma-peritoneal exchange of solutes could not be excluded.

Key-words:

• Peritoneum
• permeability
• peritoneal plasma clearance