Transperitoneal Exchange

Abstract

Aune, S. 1970. Transperitoneal Exchange. IV. The Effect of Transperitoneal Fluid Transport on the Transfer of Solutes. Scand. J. Gastroent. 5, 241-252.

The effect of a concurrent fluid flow on the transperitoneal transport of solutes has been studied in two different series:

1)

Disappearance of urea, PAH, inulin, and RISA from the peritoneal cavity was compared to previous results (1), in which the transfer of the same substances from the blood capillaries into the peritoneal compartment was measured. In the present series there was no significant absorption of RISA or mulin from the peritoneal compartment into the blood capillaries, whereas both had been found to pass through the peritoneal membrane in the opposite direction. The difference might be due to solvent drag effectuated by hydrodynamic peritoneal fluid production.

2)

Osmotic water movement into or out of the peritoneal cavity was induced by varying the osmolarity of the peritoneal solution, thereby varying the exchange of urea, PAH, inulin, and RISA proportional to the diffusibility of the solutes. Accordingly, contrary to hydrodynamic flow, osmosis has no direct dragging influence on the solute transport.

Key-words:

• Effect of fluid transport
• filtration and osmosis
• transperitoneal exchange