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Articles

Food Iron Absorption in Man

IV. Validity of the Extrinsic Tag Two-Pool Method for Measurement of Dietary Non-Heme Iron Absorption in Patients with Various Clinical Disorders

Pages 645-650 | Received 13 Feb 1973, Accepted 08 May 1973, Published online: 16 Oct 2020
 

Abstract

Björn-Rasmussen, E. Food iron absorption in man. IV. Validity of the extrinsic tag two-pool method for measurement of dietary non-heme iron absorption in patients with various clinical disorders. Scand. J. Gastroent. 1973, 8, 645–650

In 11 subjects with various clinical disorders equal absorptions were found from biologically “Fe-labeled soy-beans and from trace amounts of 59Fe Cl3 added during preparation of the meal. The results of the study indicate that a complete isotopic exchange takes place within the non-heme iron pool in subjects with gastric anacidity, rapid gastric emptying, and severe iron deficiency. It is concluded that the recently proposed extrinsic tag two-pool method to measure food iron absorption can be used in the study of iron absorption in populations where such gastroenterological or hematological disorders are prevalent.

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