Sulfonamide-Induced Chronic Liver Disease

Abstract

Tönder, M, Nordöy, A. & Elgjo, K. Sulfonamide-induced chronic liver disease. Scand. J. Gastroent. 1974, 9, 93–96.

A case with development of a clinical picture of active chronic hepatitis and biopsy findings similar to chronic aggressive hepatitis after the use of sulfonamides is reported. Provocation test with 2 tablets of sulfonamide induced within hours detoriation of the liver function. After sulfonamide medication was stopped, liver function tests normalized and eventually, also the liver biopsy showed complete regression.

Key-words::

• Chronic aggressive hepatitis
• chronic liver disease
• liver function tests and liver morphology
• sulfonamides