Effect of Three Types of Intestinal Shunt Operation on Gastric Secretion in Obesity

Abstract

Danö, P. & Vagn Nielsen, O. Effect of three types of intestinal shunt operation on gastric secretion in obesity. Scand. J. Gastroent. 1974, 9, 167-171.

In a prospective study the gastric secretion was studied before and after three types of intestinal shunt operation for obesity. In each type 48 cm of functioning small intestine was preserved, but the ratio between functioning jejunum and functioning ileum was different. A slight but significant basal hypersecretion was found in patients with 24 cm or less of functioning jejunum. Peak acid output following pentagastrin stimulation was unchanged. None of the patients developed symptoms of peptic ulcer. The mechanism of gastric hypersecretion following small bowel resection and bypass is discussed.

Key-words::

• Gastric hypersecretion
• intestinal bypass
• obesity
• types of operation