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Articles

Influence of Parathyroid Hormone and Vitamin D on Basal Gastric Secretion in Rats

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Pages 275-279 | Received 15 May 1973, Accepted 10 Oct 1973, Published online: 16 Oct 2020
 

Abstract

Öhrn, P.-G., Frenning. B., Hessman, Y., Johansson, H. & Segerström. A. Influence of parathyroid hormone and vitamin D on basal gastric secretion in rats. Scanil. J. Gastroent. 1974, 9, 275-279.

The effects of parathyroid hormone (PTH) and vitamin D were compared on basal gastric secretion in rats with chronic gastric fistulae during a 14-day period of treatment. Rats given PTH and vitamin D showed both a reduction in gastric secretory rate and in concentration of hydrogen ions in the gastric juice when compared with corresponding saline-treated controls. The pre-treatment level of total and free sialic acid in the gastric juice was unchanged in PTH-treated rats. A similar effect was caused by treatment with vitamin D. The corresponding controls showed a reduction. Gastric level of fucose showed no significant change.

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