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Articles

Effect of Glucagon on Gastric Secretion in Fistula Chickens

Pages 411-414 | Received 27 Aug 1973, Accepted 13 Nov 1973, Published online: 16 Oct 2020
 

Abstract

Burhol, P. G. Effect of glucagon on gastric secretion in fistula chickens. Scand. J. Gastroent. 1974, 9, 411-414.

The effect of intravenous injection of glucagon on basal gastric secretion was studied in 8 fistula chickens. Glucagon caused a significant and dose-dependent inhibition of gastric water and H+ secretion, whereas its inhibitory effect on the pepsin secretion was not statistically significant. It is suggested that glucagon may inhibit by a direct action on the gastric mucosa. The possibility that glucagon-like substances released from the gastrointestinal tract may participate in the physiological regulation of the gastric secretion is discussed.

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