Abstract
Danö, P. & Lenz, K. External pancreatic function following three types of intestinal shunt operation for obesity. Scand. J. Gastroent. 1974, 9, 451–455.
The external pancreatic function following a stimulation meal was investigated before, 6–12 months, and 12–24 months after three types of intestinal shunt operation as a treatment for morbid obesity in 36 patients. In everyone 48 cm of small intestine was preserved, but the ratio of functioning jejunum/ ileum was different: Type I 36 cm/12 cm. Type II 24 cm/24 cm. and Type III 12 cm/36 cm. The pancreatic function decreased in all types of operation during the first postoperative period. The reduction was least in Type III operated patients. In the second postoperative period there was an increase in pancreatic function in type I and II operated patients but a sustained reduction in type III operated patients. We suggest that the reduction of pancreatic function in the first postoperative period was due to malabsorption, and the sustained reduction in type III operated patients in the second postoperative period was due to impaired release of stimulating hormones from the bypassed jejunum.