Jejunal Morphology and Mucosal Enzyme Activity Following Intestinal Shunt Operation for Obesity

P. DanöMedical Dept. P, Division of Gastroenterology, Surgical Dept. C., Dept. of Surgical Gastroenterology, Rigshospitalet, Copenhagen, and Institute of Pathological Anatomy, University of Copenhagen, Copenhagen, Denmark

O. Vagn NielsenMedical Dept. P, Division of Gastroenterology, Surgical Dept. C., Dept. of Surgical Gastroenterology, Rigshospitalet, Copenhagen, and Institute of Pathological Anatomy, University of Copenhagen, Copenhagen, Denmark

M. PetriMedical Dept. P, Division of Gastroenterology, Surgical Dept. C., Dept. of Surgical Gastroenterology, Rigshospitalet, Copenhagen, and Institute of Pathological Anatomy, University of Copenhagen, Copenhagen, Denmark

B. JörgensenMedical Dept. P, Division of Gastroenterology, Surgical Dept. C., Dept. of Surgical Gastroenterology, Rigshospitalet, Copenhagen, and Institute of Pathological Anatomy, University of Copenhagen, Copenhagen, Denmark

Abstract

Danö, P., Nielsen, O. Vagn, Petri. M. & Jörgensen, B. Jejunal morphology and mucosal enzyme activity following intestinal shunt operation for obsity. Scand. J. Gastroent. 1976, 11, 129-134.

Jejunal biopsy in 33 patients before and after intestinal shunt operation for obesity has demonstrated that neither surface nor volume of the villi increase after surgery. Specific disaccharidase activity remained unchanged, and specific alkaline phosphatase activity increased slightly. There was a significant decrease in protein content in the postoperative biopsies. It is concluded that weight stabilization after the shunt operation is due to adaptive compensation in the ileal remnant.

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Jejunal Morphology and Mucosal Enzyme Activity Following Intestinal Shunt Operation for Obesity

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Jejunal Morphology and Mucosal Enzyme Activity Following Intestinal Shunt Operation for Obesity

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