The Disease Activity of Ulcerative Colitis and Crohn’s Disease

Abstract

Talstad, I. & Gjone, E. The disease activity of ulcerative colitis and Crohn’s disease. Scand. J. Gastroent. 1976, 11, 403-408.

The disease activity in ulcerative colitis and Crohn’s disease was studied. Parameters found to reflect the disease activity were given scores from 1 to 4. The score obtained by a patient compared with the maximum scores gives the percentage disease activity. The regressions between the percentage disease activity and the ESR in ulcerative colitis and Crohn’s disease were r=0.68 (p<0.001) and r = 0.48 (p<0.001), respectively. The different activity parameters have different time response curves explaining the occasional slight correlation. The percentage disease activity represents the mean activity of the different parameters at a given time. It is proposed to define slight, moderate, and severe ulcerative colitis or Crohn’s disease as percentage disease activity of <30, 30-70 and >70 per cent, respectively.

Key-words::

• Crohn’s disease
• erythrocyte sedimentation rate
• inflammatory bowel disease
• ulcerative colitis