Anti-colon Antibodies in Ulcerative Colitis. A Clinical Study

Abstract

Marcussen, H. Anti-colon antibodies in ulcerative colitis. A clinical study. Scand. J. Gastroent. 1976, 11, 763-767

145 consecutively admitted patients with ulcerative colitis were clinically classified. A femalermale ratio of 1.46:1 was found. Clinical symptoms and signs presumed to indicate hypersensitivity were present in 30% (95% confidence limits 23-39%). Circulating anti-colon antibodies were found in 20% (95% confidence limits 14-28%) with a female preponderance of 2.63:1. None of the following factors were significantly correlated to the presence of anti-colon antibodies: the age or sex of the patients, the degree of colonic involvement, duration of disease, age of onset, family history of disease, or manifestations of hypersensitivity associated with ulcerative colitis.

Key-words::

• Antibodies, circulating
• clinical analysis
• extra-colonic manifestations
• ulcerative colitis