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Original Articles

Additional Antacid Does Not Increase the Effect of Cimetidine in Gastric Ulcer Disease

, , , , , , , , , , , & show all
Pages 56-58 | Received 26 Jan 1983, Accepted 21 Mar 1983, Published online: 30 Apr 2018
 

Abstract

Eighty-one adult outpatients with endoscopically confirmed gastric ulceration were treated with cimetidine (1 g/day). In addition, the patients were allocated at random to either intensive antacid treatment or placebo treatment. This part of the study was double-blind. It was found that additional antacid treatment had no effect on ulcer healing and symptoms in cimetidine-treated gastric ulcer patients. The results were similar in patients with corpus ulcers and patients with prepyloric ulcers.

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