Ulcer Recurrence after Parietal Cell Vagotomy for Duodenal Ulcer

Abstract

The object of the study was to identify individual high-risk patients with regard to ulcer recurrence after parietal cell vagotomy for duodenal ulcer. The study comprises a multivariate analysis of 14 variables (age, sex, duration of symptoms, site of ulcer, pre- and post-operative acid secretion) for 37 patients with and 111 patients without recurrence 5–11 years after parietal cell vagotomy for duodenal ulcer. The data were analyzed using a supervised pattern recognition technique, SIMCA (Soft Independent Modeling of Class Analogy), which analyzes complex data as geometrical elements in a multidimensional space. We found no statistical difference between the patients with and without ulcer recurrence. Thus, no predictive value for the selection of patients liable to develop recurrent ulcer after parietal cell vagotomy was contained in the variables generally registered in current surgery.

Key words:

• Duodenal ulcer
• peptic ulcer
• vagotomy, proximal gastric