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Original Articles

Gastric Acid Secretion and Duodenal Ulcer Healing during Treatment with Omeprazole

Pages 882-884 | Received 05 Sep 1983, Accepted 16 Jan 1984, Published online: 30 Apr 2018
 

Abstract

Twenty-seven duodenal ulcer patients were treated with omeprazole, 40 mg daily for 4 weeks. The peak acid output to pentagastrin measured 24 h after dosing was reduced by 54% on day 3 of the study and by 74% on day 14. The ulcers in 25 of 26 patients had healed by the end of the treatment period, and 1 patient was unable to attend the final endoscopy. Ulcer symptoms were relieved rapidly. The drug was well tolerated, and few adverse reactions were reported.

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