Influence of Fiber on Acidity, Pepsin, and Bile Acids in Human Gastric Juice in Vitro

Abstract

The effect of a fiber-enriched wheat bran product, Fiberform®, and a guar gum, Guarem®, on gastric juice acidity, pepsin, and bile acid concentration was studied in vitro. Fiberform had a slight acid-binding capacity. The fiber preparation did not bind pepsin. Both products bound bile acids. With Fiberform the amount of bile acids bound was proportional to the amount of fiber and most pronounced at low pH and high bile acid concentration.

Key words:

• Bile acids
• fiber
• gastric juice acidity
• pepsin