157
Views
5
CrossRef citations to date
0
Altmetric
Short Report

Mallory Weiss syndrome is not associated with hiatal hernia: a matched case–control study

, , , , &
Pages 462-464 | Received 23 Nov 2016, Accepted 28 Nov 2016, Published online: 22 Dec 2016
 

Abstract

Background/objective: Hiatal hernia is considered to be a predisposing factor to develop Mallory-Weiss Syndrome (MWS). No large case–control studies verifying this hypothesis have been conducted.

Methods: We reviewed all esophagogastroduodenoscopies with findings of MWS (n = 2342) in a national database and compared with age and gender-matched controls (n = 9368). Demographics, endoscopic characteristics and presence of a hiatal hernia were compared between both groups. Average age was 56.7 ± 18.6 years, and 72.4% were male.

Results: Hiatal hernia was more common in controls, and no significant difference was seen in a multivariate analysis.

Conclusion: Dynamic changes inducing mucosal tension are more relevant determinants to develop MWS than gastro-esophageal junction location alone.

Acknowledgements

The data from the CORI reported here were supplied by the NIDDK Central Repositories. This manuscript was not prepared in collaboration with the CORI group and does not necessarily reflect the opinions or views of the CORI group, the NIDDK Central Repositories, or the NIDDK.

Disclosure statement

The authors declare no conflict of interest.

Additional information

Funding

The CORI v3 Database is supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). D. A. Sussman is supported in part by grants from the Center for AIDS Research (CFAR) at the University of Miami – Miller School of Medicine, funded by a grant from the National Institutes of Health (P30AI073961), American Cancer Society and the Florida Department of Health.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.