Performance of chromoendoscopy and narrow-band imaging in the diagnosis of gastric intestinal metaplasia

Abstract

Background/Aims

Chromoendoscopy and narrow-band imaging (NBI) have been reported to aid in the diagnosis of gastric intestinal metaplasia (GIM). This study aimed to assess the diagnostic validity of chromoendoscopy combined with NBI in the diagnosis of GIM in Vietnamese.

Methods

A cross-sectional study was carried out on patients with dyspeptic symptoms who underwent esophagogastroduodenoscopy (EGD) at the University Medical Center at Ho Chi Minh City. We compared the detection rates of GIM in the group of patients examined with white-light endoscopy (WLE) alone and those examined with WLE in combination with chromoendoscopy and NBI.

Results

A total of 374 patients have been recruited. The additional GIM detection rate after chromoendoscopy combined with NBI was 8.6% (95% confidence interval [CI]: 4.3 − 12.8), p < .005. The rate of GIM within the group of patients biopsied under the guidance of chromoendoscopy combined with NBI was statistically significantly higher than in the group with WLE alone with a distinct rate of 14.4% (95% CI: 6.3 − 2.6), p = .001.

Conclusions

Chromoendoscopy combined with NBI helped to detect the GIM lesions missed by WLE and was a more reliable endoscopic method for the diagnosis of GIM.

Keywords:

• Chromoendoscopy
• narrow-band imaging
• endoscopy
• intestinal metaplasia
• Vietnam

Acknowledgments

The authors thank Dr. Tran Kieu Mien, vice president of the Vietnam Association of Gastroenterology, and their staff at the Department of Endoscopy, University Medical Center at Ho Chi Minh City for their support.

Author contributions

Conceptualization: DTQ; Data curation: NVTH and DTNN; Formal analysis: NVTH, NLBD and QDL; Investigation: NVTH, NLBD, QDL, DTNN and HML; Resources: NQL; Supervision: DTQ; Writing-original draft: NVTH; Writing-review and editing: TH, DTQ and NQL.

Disclosure statement

The authors have no potential conflicts of interest.