Out of sight for the endoscopist? Gastrointestinal bleeding after aortic repair

Abstract

Background and study aim

Secondary Aortoenteric Fistulas (sAEF) are difficult to diagnose and usually result in fatal gastrointestinal (GI) bleeding following aortic repair. Outcomes are largely dependent on a timely diagnosis, but AEFs remain challenging to identify endoscopically and are usually diagnosed on computed tomography (CT) scans. The aim of our study was optimize diagnosis of AEF by identifying patients developing GI bleeding after aortic repair, investigate their clinical course and identify factors specific to different bleeding sources.

Methods

A retrospective, single-center study capturing all patients developing upper or lower GI bleeding after aortic surgery between January 2009 and March 2020 was performed. Electronic health records were screened for diagnostic codes of the relevant procedures. Bleeding was classified into three groups: AEF with demonstrable fistula, ischemic – macroscopic ulceration plus histological confirmation or imaging and “other” due to other recognized conventional cause, such as peptic ulcer disease.

Results

47 GI bleeding episodes in 39 patients were identified. Of these, 10 episodes (21%) were caused by AEF, 16 (34%) by ischemic ulceration and 21 (45%) due to other causes. Patients with AEF exhibited more frequent hemodynamic instability requiring vasopressors and had higher mortality, while ischemic ulcerations were associated with more recent operation or hypotensive episode.

Conclusions

GI bleeding complications are uncommon following aortic surgery. AEF and ischemic ulceration are however frequent bleeding causes in this cohort. In patients presenting with fulminant bleeding, primary CT-scanning should be considered.

Keywords:

• Aortoenteric Fistula (AEF); gastrointestinal bleeding; ischemic ulceration; aortic repair; endoscopy

Acknowledgements

The authors are grateful to Mrs. Christine Krehut, Hannover, Germany for her help in searching the administrative database.

Disclosure statement

The authors declare that there is no conflict of interest.