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Research Article

Inhibitory Effect of 17ß-Estradiol on Growth and the Polyamine Metabolism of a Human Gastric Carcinoma Cell Line (HGC-27)

Pages 79-84 | Published online: 08 Jul 2009
 

Abstract

Background: Estrogens may, by means of their receptors, modulate the growth of several tumors including gastrointestinal neoplasms. This control may occur through interaction with other molecules such as polyamines. An inverse relation between polyamine levels and the estrogen receptorial content has previously been demonstrated in vivo in human gastric carcinoma. The aim of the present study was to evaluate the effects of 17

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