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Research Article

The Relation between Antioxidant Status and Alterations in Fatty Acid Profile in Patients with Crohn Disease and Controls

Pages 1108-1116 | Published online: 08 Jul 2009
 

Abstract

Background: A diminished antioxidant defence and alterations in the fatty acid profile may play a role in the pathophysiology of inflammation in Crohn disease (CD). Methods: Antioxidant status (serum antioxidant vitamins and minerals, glutathione peroxidase, and superoxide dismutase activity), disease activity, dietary intake, and the fatty acid profile in plasma and erythrocyte phospholipids were studied in patients with active CD (n = 12), inactive CD (n = 50), and controls (n

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