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Abstract
We retrospectively reviewed the effects on the erythrocyte mean corpuscular volume (MCV) of the use of stavudine - including antiretroviral regimens in both zidovudine-naive and zidovudine-experienced HIV-infected patients. Macrocytosis was commonly observed among patients on stavudine-based regimens although the MCV usually stabilized at a lower level than that observed with zidovudine.