Painful Neuropathy Vasculitis in 2 Patients with Long-Standing Human Immunodeficiency Virus-1 Infection

Sergio Ferrari Clinical Neurology, Department of Neurological and Visual Sciences, Verona

Massimiliano Lanzafame Infectious Diseases, Department of Pathology, University of Verona, VeronaCorrespondence[email protected]

Federica Faggian HIV Screening Centre, ULSS20, Verona

Marina Malena Clinical Neurology, Department of Neurological and Visual Sciences, Verona

Mario Cruciani Infectious Diseases, Department of Pathology, University of Verona, Verona

Tiziana Cavallaio HIV Screening Centre, ULSS20, Verona

Nicola Rizzato Clinical Neurology, Department of Neurological and Visual Sciences, Verona

Ercole Concia Infectious Diseases, Department of Pathology, University of Verona, Verona

Sandro Vento HIV Screening Centre, ULSS20, Verona

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Abstract

We describe 2 most unusual cases of distal symmetrical painful polyneuropathy in patients with long-standing HIV-1 infection well controlled by HAART. Sural nerve biopsies revealed vasculitis in both cases and steroid therapy led to resolution of symptoms not influenced by analgesics and anti-inflammatory drugs. These unusual cases outline the importance of nerve biopsies in order to reach a diagnosis.

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Painful Neuropathy Vasculitis in 2 Patients with Long-Standing Human Immunodeficiency Virus-1 Infection

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Painful Neuropathy Vasculitis in 2 Patients with Long-Standing Human Immunodeficiency Virus-1 Infection

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