Successful Long-term Application of Highly Purified Natural Interferon-alpha (Multiferon®) after Preceding Interferon Approaches in a Chronic Hepatitis C Patient with Thrombocytopenia

Eugen Musch Department of General Internal Medicine, Marienhospital Bottrop gGmbHCorrespondence[email protected]

Mouhamad Malek Department of Internal Medicine, Medical Hospital, University of Bonn

Harald von Eick Scientific Advisor, ViraNative AB

Angeliki Chrissafidou Department of General Internal Medicine, Marienhospital Bottrop gGmbH

Abstract

Treatment approaches with recombinant IFN-α2b and natural IFN-β in a patient with chronic hepatitis C (genotype 1b) and cirrhosis had, in both cases, to be terminated prematurely due to breakthrough phenomena and thrombo-leucocytopenia up to WHO grade 3. After the patient was switched to highly purified natural IFN-α (Multiferon®) the thrombocyte and leukocyte counts increased significantly, and sustained complete biochemical and virological response could be achieved.

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Successful Long-term Application of Highly Purified Natural Interferon-alpha (Multiferon®) after Preceding Interferon Approaches in a Chronic Hepatitis C Patient with Thrombocytopenia

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Successful Long-term Application of Highly Purified Natural Interferon-alpha (Multiferon®) after Preceding Interferon Approaches in a Chronic Hepatitis C Patient with Thrombocytopenia

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