Contribution of procalcitonin to occult bacteraemia detection in children

Christele Gras-Le Guen From the Paediatric Intensive Care Unit, CHU, Nantes, France; UPRES EA, School of Medicine, Nantes, FranceCorrespondence[email protected]

Caroline Delmas From the Paediatric Intensive Care Unit, CHU, Nantes, France

Elise Launay From the Paediatric Intensive Care Unit, CHU, Nantes, France

Jocelyne Caillon UPRES EA, School of Medicine, Nantes, France; Laboratory of Bacteriology, CHU, Nantes, France

Virginie Loubersac Laboratory of Biochemistry, CHU, Nantes, France

Georges Picherot Pediatric Emergency Department, CHU, Nantes, France

J. Christophe Roze From the Paediatric Intensive Care Unit, CHU, Nantes, France

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Abstract

We conducted a prospective study in 215 children, 3 to 36 months of age, presenting with fever ≥39°C without obvious origin, in order to evaluate the diagnostic value of procalcitonin (PCT) in detection of occult bacteraemia. PCT associated with white blood cell count constitutes an efficient screening method with sensitivity 100%, specificity 61.9% and positive and negative likelihoods ratios of 2.62 and 0, respectively

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Contribution of procalcitonin to occult bacteraemia detection in children

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Contribution of procalcitonin to occult bacteraemia detection in children

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