Enterovirus 71 in Taiwan, 2004–2006: Epidemiological and virological features

Kuan-Ying Huang From the Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan

Xiaowei Zhang Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, P. R. China

Po-How Chung From the Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan

Kuo-Chien Tsao Department of Clinical Pathology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan

Tzou-Yien Lin From the Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan

Lin-Hui Su Department of Clinical Pathology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan

Cheng-Hsun Chiu From the Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University College of Medicine, Taoyuan, TaiwanCorrespondence[email protected]

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Abstract

We report unusual cases of myocarditis caused by enterovirus 71 (EV71) and a declining trend in the incidence of EV71 in Taiwan since 2005. Furthermore, phylogenetic analysis of the 5′ untranslated region, VP4, and VP1 genes of EV71 isolates in 2004–2005 revealed a divergent phylogeny from the previous Taiwanese isolates. No obvious phylogenetically distinct clones or clusters were found related to varying degrees of disease severity or clinical manifestations.

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Enterovirus 71 in Taiwan, 2004–2006: Epidemiological and virological features

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Enterovirus 71 in Taiwan, 2004–2006: Epidemiological and virological features

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