Erythromycin resistance caused by erm(A) subclass erm(TR) in a Danish invasive pneumococcal isolate: Are erm(A) pneumococcal isolates overlooked?

Lotte Lambertsen From the Neisseria and Streptococcus Reference, Department for Bacteriology, Mycology and Parasitology, Statens Serum Institute, CopenhagenCorrespondence[email protected]

Kim Ekelund From the Neisseria and Streptococcus Reference, Department for Bacteriology, Mycology and Parasitology, Statens Serum Institute, Copenhagen

Dennis S. Hansen Department of Clinical Microbiology, Hillerød Hospital, Hillerød

Margit Kaltoft From the Neisseria and Streptococcus Reference, Department for Bacteriology, Mycology and Parasitology, Statens Serum Institute, Copenhagen

Jens J. Christensen From the Neisseria and Streptococcus Reference, Department for Bacteriology, Mycology and Parasitology, Statens Serum Institute, Copenhagen

Anette M. Hammerum National Centre for Antimicrobials and Infectious Control, Statens Serum Institute, Copenhagen, Denmark

Abstract

Erm(A) is rarely reported as erythromycin resistance determinant in pneumococci. One invasive erm(A) isolate was initially tested intermediate erythromycin resistant using E-test. However, upon re-testing it was resistant, thus close to the breakpoint value. This may be a reason why erm(A) only rarely is reported to cause resistance in pneumococci.

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Erythromycin resistance caused by erm(A) subclass erm(TR) in a Danish invasive pneumococcal isolate: Are erm(A) pneumococcal isolates overlooked?

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Erythromycin resistance caused by erm(A) subclass erm(TR) in a Danish invasive pneumococcal isolate: Are erm(A) pneumococcal isolates overlooked?

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