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Methicillin-resistant Staphylococcus aureus (MRSA) cultures were obtained from 288 mother-infant pairs. A questionnaire given to mothers and medical record review assessed risk factors for colonization. Only 2.1% of mothers and 0.7% of infants carried MRSA. There were no identical MRSA mother-newborn pairs. MRSA colonization by expectant mothers is uncommon and transmission to newborns from vaginal delivery did not occur.
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