Actinobacillus (Aggregatibacter) actinomycetemcomitans (HACEK) identified by PCR/16S rRNA sequence analysis from the heart valve in a patient with blood culture negative endocarditis

Katarina Westling From the Division of Infectious Diseases, Department of Medicine, Karolinska University Hospital, and Karolinska Institute,Correspondence[email protected]

Martin Vondracek Division of Clinical Microbiology, Karolinska University Hospital and CMM, Karolinska Institute, Stockholm, Sweden

Abstract

We report a case of infective endocarditis caused by Actinobacillus actinomycetemcomitans (Aggregatibacter actinomycetemcomitans) from the HACEK group diagnosed by PCR/16S from the heart valve. Multiple blood cultures and cultures from heart valve were negative and cardiac surgery was performed due to therapeutic and cardiac failures. Molecular biological methods are useful in such a patient, to choose an optimal antibiotic treatment post-surgery.

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Actinobacillus (Aggregatibacter) actinomycetemcomitans (HACEK) identified by PCR/16S rRNA sequence analysis from the heart valve in a patient with blood culture negative endocarditis

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Actinobacillus (Aggregatibacter) actinomycetemcomitans (HACEK) identified by PCR/16S rRNA sequence analysis from the heart valve in a patient with blood culture negative endocarditis

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