A fatal case of encephalitis associated with Chikungunya virus infection

Stefania Casolari From the Department of Infectious Diseases, Ospedale Santa Maria, Ravenna

Elisabetta Briganti From the Department of Infectious Diseases, Ospedale Santa Maria, Ravenna

Miriam Zanotti From the Department of Infectious Diseases, Ospedale Santa Maria, Ravenna

Tiziano Zauli From the Department of Infectious Diseases, Ospedale Santa Maria, Ravenna

Loredana Nicoletti Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanità, Rome, Italy

Fabio Magurano Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanità, Rome, Italy

Claudia Fortuna Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanità, Rome, Italy

Cristiano Fiorentini Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanità, Rome, Italy

Maria Grazia Ciufolini Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanità, Rome, Italy

Giovanni Rezza Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanità, Rome, ItalyCorrespondence[email protected]

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Abstract

An outbreak of Chikungunya fever occurred in north-east Italy in the summer of 2007. Only 1 fatal case was observed, in an 83-y-old male hospitalized with encephalitis. Viral genome was detected at high level (1.5×10⁸ copies/ml) in the cerebrospinal fluid 7 d after symptoms onset.

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A fatal case of encephalitis associated with Chikungunya virus infection

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A fatal case of encephalitis associated with Chikungunya virus infection

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