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Scandinavian Journal of Urology and Nephrology Volume 35, 2001 - Issue 1
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Research Article

Histo-blood Group A Antigen Expression in Pig Kidneys: Implication for ABO Incompatible Pig-to-Human Xenotransplantation

Lennart Rydberg, Johan Mölne, Valeri Strokan, Christian T. Svalander, Michael E. Breimer Department of Clinical Chemistry and Transfusion Medicine, Sahlgrenska University Hospital, Göteborg, Sweden; Department of Pathology, Sahlgrenska University Hospital, Göteborg, Sweden; Departments of Pathology and Surgery, Sahlgrenska University Hospital, Göteborg, Sweden; Department of Surgery, Sahlgrenska University Hospital, Göteborg, Sweden
Pages 54-62 | Published online: 09 Jul 2009
 
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Abstract

Objective: There is a relative shortage of donor organs for clinical transplantation, and the use of animal organs is being considered. A clinical trial was performed connecting pig kidneys to the circulation of a dialysis patient. Material and Methods: A pig kidney was, after plasmapheresis, extracorporeally connected to the circulation of a volunteer dialysis patient. The patient was of blood group B and the pig of blood group A. Results:

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