Severe Symptomatic Osteoporosis in Patients on Androgen Deprivation Therapy for Prostatic Carcinoma

Abstract

We report 3 patients referred to the bone clinic after spinal fractures. Dual energy X-ray absorptiometry showed severe osteoporosis. Each patient was found to have a history of prostatic carcinoma and long-term treatment with goserelin. We suggest that all patients who have received androgen deprivation therapy for more than 1 year should be evaluated by bone densitometry.

• Androgen Antagonists
• Fractures
• Goserelin
• Hypogonadism
• Lh-RH
• Osteoporosis
• Prostate Neoplasms