In Vitro Responses of Detrusor Smooth Muscle to Stretch and Relaxation

Abstract

In vitro studies subjecting detrusor smooth muscle to stretch and relaxation support the concept that bladder tonus and accommodation result from physical properties of the bladder wall and are not dependent upon neural activity. The properties of automaticity, hysteresis and length/tension relationships of smooth muscle seen clinically and in vivo are also seen in vitro.