Intermittent Androgen Suppression: Too Good to be True?

Abstract

The progression of metastatic prostate cancers to an androgen-independent state removes the possibility of further androgen therapy. In response to this, new treatments that do not cause the loss of androgen sensitivity have been sought. Intermittent androgen suppression therapy, an adaptation of the previously used androgen ablation techniques, has shown great promise, comparing favourably with continuous androgen deprivation in pilot studies. It may, therefore, prove to be an excellent treatment, both individually and in combination, although further studies are required.