Sequential Injection Analysis (SIA) for Arsenic Speciation by Capillary Electrophoresis Hyphenated to Inductively Coupled Plasma Sector Field Mass Spectrometry (CE–ICP–SFMS)

ABSTRACT

Sequential injection analysis (SIA) is proposed for managing microvolumes of sample and arsenic species solutions for speciation analysis by capillary electrophoresis focusing on the reduction of hazardous waste residues. An electronically controlled hydrodynamic injector was projected to introduce microvolumes of solutions prepared by SIA into the CE capillary with precision better than 2%. The determination of arsenite, arsenate, monomethylarsonic acid, dimethylarsinic acid, and arsenobetaine was performed from 50 µL volumes of lyophilized urine and extract of shrimp with the system hyphenated to inductively coupled plasma mass spectrometry (CE–ICP–SFMS).

KEYWORDS:

• arsenic species
• capillary electrophoresis
• hazardous waste
• inductively coupled plasma mass spectrometry
• sequential injection analysis

ACKNOWLEDGMENTS

The authors thank CNPq and FINEP for financial support.

Notes

N = 5.

An invited paper submitted to a special issue on Green Spectroscopy and Analytical Techniques, organized by Professor Miguel de la Guardia, of the Department of Chemistry, University of Valencia, Spain, and Professor Arabinda Kumar Das, of the Department of Chemistry, University of Burdwan, West Bengal, India.