¹³C NMR Chemical Shifts Substituent Effects of (E)- and (Z)-N-ethyl-N-Methylamides

Abstract

Carbon-13 NMR chemical shifts of a series of (E)- and (Z)-N-ethyl-N-methylamides [RC(O)NEtMe, R=H, Me, Et, i-Pr, t-Bu, CF₃, ClCH₂, Cl₂CH, Cl₃C, BrCH₂, Br₂CH, Br₃C and ICH₂] are reported. The α-carbon and carbonyl carbon chemical shifts are correlated with the empirical α-substituent effect and Charton's electrical parameter ([sgrave]_I), respectively. The N-alkyl carbon resonances were attributed mainly to the γ- and δ-effects of R.

Key Words:

• ¹³C NMR of Amides
• (E)- and (Z)-N-Ethyl-N-methylamides
• ¹³C NMR Substituent Effects