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Spectroscopy Letters
An International Journal for Rapid Communication
Volume 30, 1997 - Issue 2
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Original Articles

Antimalarial 1,2,4-Trioxanes Related to Artemisinin: Rules for Assignment of Relative Stereochemistry in Diversely Substituted Analogs

Chang Ho Oh Department of Chemistry, Zanvyl Krieger School of Arts and Sciences, The Johns Hopkins University, Baltimore, MD, 21218
,
Dasong Wang Department of Chemistry, Zanvyl Krieger School of Arts and Sciences, The Johns Hopkins University, Baltimore, MD, 21218
,
Jared N. Cumming Department of Chemistry, Zanvyl Krieger School of Arts and Sciences, The Johns Hopkins University, Baltimore, MD, 21218
&
Gary H. Posner Department of Chemistry, Zanvyl Krieger School of Arts and Sciences, The Johns Hopkins University, Baltimore, MD, 21218
Pages 241-255 | Received 15 Jul 1996, Accepted 23 Aug 1996, Published online: 21 Aug 2006
 
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Abstract

A series of rules has been developed, using mainly 1D and 2D NMR spectroscopy, for identification of relative stereochemistry in a variety of substituted antimalarial 1,2,4-trioxanes.

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