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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 30, 2000 - Issue 13
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Original Articles

Synthesis of Novel Spin Labeled Analogues of N-(Trifluoroacetyl)Daunorubicin

Shao-Jun Xu Department of Chemistry, Zhejiang University, Hangzhou, 310027, PR China
,
Cheng Ma Department of Chemistry, Zhejiang University, Hangzhou, 310027, PR China
,
Yan-Guang Wang Department of Chemistry, Zhejiang University, Hangzhou, 310027, PR China
&
Yao-Zu Chen Department of Chemistry, Zhejiang University, Hangzhou, 310027, PR China
Pages 2375-2382 | Received 23 Jul 1999, Published online: 04 Dec 2007
 
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Abstract

Three novel spin labeled N-(trifluoroacetyl) daunorubicins 6–8 have been synthesized under mild reaction condition in good yields. The antitumor activity of compound 6 and 8 were evaluated in vitro.

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