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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 30, 2000 - Issue 21
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Original Articles

An Improved Synthesis of Inosine 3′-Phosphoramidite

Jasenka Matulic-Adamic Department of Chemistry & Biochemistry, Ribozyme Pharmaceuticals Inc., 2950 Wilderness Place, Boulder, CO, 80301, USA
&
Leonid Beigelman Department of Chemistry & Biochemistry, Ribozyme Pharmaceuticals Inc., 2950 Wilderness Place, Boulder, CO, 80301, USA
Pages 3963-3969 | Received 13 Feb 2000, Published online: 04 Dec 2007
 
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Abstract

A protocol for the efficient conversion of inosine into its 3′-phosphoramidite synthon for solid phase oligonucleotide synthesis has been developed.

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